Taking five or more medications – this is part of the daily routine of many, especially elderly people. But polymedication increases the risk of drug-related problems. This is where the pharmaceutical service „Extended medication counselling for polymedication“ comes in. This comprehensive guide shows how to establish and implement such knowledge in the pharmacy: ■ Part A explains the legal and contractual basis of the service. In addition, the publication highlights the risks of polymedication, drug-related problems and goals, and the benefits of the service for the stakeholders involved in the pharmacy, the doctor‘s practice, and for the patients themselves. ■ Part B is dedicated to the organisation in the pharmacy: team preparation, quality management, required documents, consulting and workplaces, and staff qualification. Aspects such as time management, patient recruitment and public liability are also considered. ■ Part C describes the individual process steps flanked by aids such as work tables, checklists, sample texts (for download at www.Online-PlusBase.de) and a comparison table for supporting AMTS software tools, including screenshots. ■ Part D offers case studies, including the initiation of extended medication counselling, the pharmaceutical AMTS review (software-supported), solution paths and communication (including formulation examples) with the various stakeholders involved. A medication analysis promotes drug therapy safety, strengthens customer loyalty and creates new opportunities for interdisciplinary cooperation with the medical profession – good reasons for starting immediately!