At a time when cyberattacks and data breaches are becom- ing a daily threat, safeguarding your pharmacy has never been more essential. In addition to safeguarding sensitive patient data, it is crucial to ensure the operational continuity of your pharmacy. Both preventing economic losses and ensuring the uninterrupted supply of medicines to the population are crucial. As pharmacies are part of the critical infrastructure, high cyber resilience and robust business continuity management are now essential. The authors offer a practical introduction to essential aspects of IT security and clarify key legal considerations. Practical recommendations are provided, including strate- gies to protect against attacks and data loss, as well as guidance on how to respond to (cyber) emergencies. This resource enables pharmacies to develop a customised security concept and implement a comprehensive Informa- tion Security Management System (ISMS) step by step. Target group: Pharmacy owners, pharmacy employees, pharmaceutical technicians, pharmaceutical sales assistants, staff, pharmacists