New York City in the sixties: the city that never sleeps, because they have plenty of pills for that. And in between, a girl from West Berlin.

Mona is young, pretty and recently moved to New York to make a career for herself. The city that never sleeps hasn't been waiting for her. Although she does quickly meet two men: East Coast aristocrat Sidney, and dark-haired bohemian Adam. Torn between the two, Mona drifts through a world that is supplied with "vitamin injections" by Max Jacobson, aka Dr Feelgood, who fled from the Nazis in Berlin.

And so a second thread weaves its way into the story: star photographer Mark Shaw, one of Dr Feelgood’s patients, is found dead in his apartment one day. A coroner starts investigating. There is a lot to be examined, and it involves the rich and beautiful and powerful all the way to the White House …